Number of reported cases of RSV, COVID-19 and flu in 2025-2026 (Week 45); Credit: MSSS

On Thursday 12 November 2026, Luxembourg's Ministry of Health and Social Security published the Health Directorate's latest weekly report on major acute respiratory infections, covering COVID-19, influenza and respiratory syncytial virus (RSV) from Monday 2 to Sunday 8 November 2026 (week 45).

COVID-19 / SARS-CoV-2 cases increase

The number of positive COVID-19 cases increased from 83 to 110, representing a 33% increase compared to the previous week.

Meanwhile, the viral concentration detected in wastewater decreased.

The latest available sequencing data reveals that the XFG variant (49.4%) and the RW.1 variant (20.8%) are predominant.

Flu cases remain at a low level

During week 45, the number of flu cases reported by laboratories increased from 64 to 65 compared to the previous week. The number of cases therefore remains broadly stable and at a level comparable to that recorded during the same period in previous years.

During the last week, influenza A accounted for 92% of typed cases, while influenza B represented 8%.

Low level of RSV cases

The number of RSV cases reported by laboratories remained low, with thirteen cases reported during week 45, compared to five the previous week.

The number of cases remains slightly below that recorded during the same period in previous years. The coming weeks will determine whether this marks the beginning of an upward trend.